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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
20.3
Human Site:
Y545
Identified Species:
37.22
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
Y545
K
T
Y
P
D
D
T
Y
R
L
S
R
L
L
L
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
Y620
K
T
Y
P
D
D
T
Y
R
L
S
R
L
L
L
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
Y498
V
K
L
C
I
D
G
Y
E
Y
A
Y
L
K
A
Dog
Lupus familis
XP_854792
605
67422
Y547
K
T
Y
P
D
D
T
Y
R
L
S
R
L
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
R533
T
Y
P
D
D
T
Y
R
L
S
R
L
L
L
R
Rat
Rattus norvegicus
Q8VIJ4
590
65509
R533
T
Y
P
D
D
T
Y
R
L
S
R
L
L
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
L505
Y
P
D
D
T
Y
R
L
S
R
L
L
L
R
L
Chicken
Gallus gallus
O42101
501
57084
T445
N
A
A
L
L
D
Y
T
M
C
N
Y
P
Q
Q
Frog
Xenopus laevis
Q66J63
637
70793
Y579
K
T
Y
P
E
D
T
Y
R
L
S
R
L
L
L
Zebra Danio
Brachydanio rerio
Q06725
411
45463
S355
S
Q
Y
P
N
Q
P
S
R
F
G
K
L
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
T487
T
Q
Y
P
N
Q
P
T
R
F
G
K
L
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
E538
S
S
V
N
I
A
A
E
R
F
S
R
I
L
Q
Sea Urchin
Strong. purpuratus
Q26622
583
63834
L527
F
S
K
L
L
L
R
L
P
T
L
R
L
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
100
20
100
N.A.
20
20
N.A.
13.3
6.6
93.3
40
N.A.
40
N.A.
26.6
20
P-Site Similarity:
100
100
26.6
100
N.A.
20
20
N.A.
13.3
13.3
100
53.3
N.A.
53.3
N.A.
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
8
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
24
39
47
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
24
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
16
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
16
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
31
8
8
0
0
0
0
0
0
0
0
16
0
8
0
% K
% Leu:
0
0
8
16
16
8
0
16
16
31
16
24
85
77
54
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
16
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
16
47
0
0
16
0
8
0
0
0
8
0
0
% P
% Gln:
0
16
0
0
0
16
0
0
0
0
0
0
0
8
16
% Q
% Arg:
0
0
0
0
0
0
16
16
54
8
16
47
0
8
16
% R
% Ser:
16
16
0
0
0
0
0
8
8
16
39
0
0
0
8
% S
% Thr:
24
31
0
0
8
16
31
16
0
8
0
0
0
0
0
% T
% Val:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
16
47
0
0
8
24
39
0
8
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _